• 
  Deportivo Riestra – Newell`s

  16 February

• 
  Instituto – Central

  16 February

• 
  Rosario Central – Barracas

  16 February

• 
  Boca Juniors – Atletico

  15 February

• 
  Gimnasia y Esgrima LP – Estudiantes

  15 February

• 
  Sint-Truidense – Zulte

  15 February

• 
  Anderlecht – RAAL

  15 February

• 
  Colo Colo – Union

  16 February

• 
  Nublense – Audax

  15 February

• 
  Fortaleza CEIF – Boyaca

  16 February

• 
  Deportivo Cali – Atletico

  16 February

• 
  Deportes Tolima – Once

  15 February

• 
  Lyon – Nice

  15 February

• 
  RB Leipzig – Wolfsburg

  15 February

• 
  Cagliari – Lecce

  16 February

• 
  Napoli – Roma

  15 February

• 
  Torino – Bologna

  15 February

• 
  SKA – Salavat Yulaev

  16 February

• 
  Admiral – Amur

  16 February

• 
  Santos Laguna – Mazatlan

  16 February

• 
  Cruz Azul – UANL

  15 February

• 
  Rio Ave – Moreirense

  16 February

• 
  Sporting – Famalicao

  15 February

• 
  AVS – Estoril Praia

  15 February

• 
  Dinamo Bucharest – Unirea

  16 February

• 
  Hermannstadt – CFR Cluj

  16 February

• 
  U Craiova – FCSB

  15 February

• 
  Girona – Barcelona

  16 February

• 
  Mallorca – Real Betis

  15 February

• 
  Levante – Valencia

  15 February

• 
  Kasimpasa – Fatih

  16 February

• 
  Basaksehir – Besiktas

  15 February

• 
  Dubai – Bosna Royal

  16 February

• 
  Partizan – Buducnost

  15 February

• 
  FMP – Mega Bemax

  15 February

• 
  Seoul – Sanfrecce

  17 February

• 
  Machida Zelvia – Chengdu

  17 February

• 
  Al-Shorta – Al-Duhail

  16 February

• 
  Al-Hilal Riyadh – Al

  16 February

• 
  Al Ahli Jeddah – Shabab

  16 February

• 
  Sharjah – Nasaf

  16 February

• 
  San Martin – La Union

  17 February

• 
  San Lorenzo – Obera

  17 February

• 
  Boca Juniors – Ciclista

  17 February

• 
  Sydney – Oakland

  17 February

• 
  Gabala – Sabah

  16 February

• 
  Shamakhi – Turan Tovuz

  16 February

• 
  Gomel – Slavutych

  16 February

• 
  Zeljeznicar – Rudar

  16 February

• 
  Fluminense – Bangu

  16 February