• 
  River Plate – Banfield

  27 February

• 
  Rio Cuarto – Huracan

  27 February

• 
  Sarmiento – Union

  27 February

• 
  Racing – Independiente R

  27 February

• 
  Santos-SP – Vasco

  27 February

• 
  Once Caldas – Boyaca

  28 February

• 
  Millonarios – Deportivo

  27 February

• 
  Bournemouth – Sunderland

  28 February

• 
  Wolverhampton – Aston

  28 February

• 
  Crystal – Zrinjski

  27 February

• 
  AZ – Noah

  27 February

• 
  Lech Poznan – KuPS

  27 February

• 
  Lausanne – Sigma

  27 February

• 
  Fiorentina – Jagiellonia

  26 February

• 
  Celje – Drita

  26 February

• 
  Samsunspor – Shkendija

  26 February

• 
  Nottingham – Fenerbahce

  27 February

• 
  Bologna – Brann

  27 February

• 
  Celta – PAOK

  27 February

• 
  Genk – Dinamo Zagreb

  27 February

• 
  Stuttgart – Celtic

  26 February

• 
  Crvena Zvezda – Lille

  26 February

• 
  Viktoria – Panathinaikos

  26 February

• 
  Ferencvaros – Ludogorets

  26 February

• 
  Augsburg – Cologne

  27 February

• 
  Parma – Cagliari

  27 February

• 
  V-Varen Nagasaki – Cerezo

  28 February

• 
  Gamba Osaka – Shimizu

  28 February

• 
  Tokyo – Kashiwa Reysol

  28 February

• 
  Urawa Reds – Kashima

  28 February

• 
  Yokohama Marinos – Tokyo

  28 February

• 
  Vissel Kobe – Avispa

  27 February

• 
  Sanfrecce Hiroshima – Kyoto

  27 February

• 
  Machida Zelvia – JEF

  27 February

• 
  Severstal – Torpedo NN

  27 February

• 
  Sochi – Dinamo Mn

  27 February

• 
  CSKA – Kunlun RS

  27 February

• 
  Avtomobilist – Ak Bars

  27 February

• 
  Avangard – Metallurg Mg

  27 February

• 
  SKA – Dynamo Msk

  26 February

• 
  Spartak M – Admiral

  26 February

• 
  Tijuana – Pumas

  28 February

• 
  Juarez – Atlas

  28 February

• 
  Queretaro – Santos

  28 February

• 
  Mazatlan – Pachuca

  28 February

• 
  Sporting – Estoril Praia

  28 February

• 
  Porto – Arouca

  27 February

• 
  Krasnodar – Rostov

  28 February

• 
  Orenburg – Akron

  28 February

• 
  Zenit – Baltika

  27 February